NeoStrata

NeoStrata was founded in 1988 by dermatologist Dr. Van Scott and dermatopharmacologist Dr. Ruey Yu, who invented alpha and polyhydroxy acid technology. The brand holds over 110 patents and has published nearly 250 clinical studies and journal papers.

13 products reviewed

83/100 Score

NeoStrata Sheer Physical Protection SPF 50 tinted mineral sunscreen tube

Mineral Shield Plus Antioxidants

NeoStrata sunscreen

Sheer Physical Protection SPF 50

A mineral sunscreen that thinks beyond UV — NeoStrata's SPF 50 layers zinc oxide and titanium dioxide with their proprietary PHAs, green tea antioxidants, and iron oxide tint to create a multi-defense environmental shield. Cosmetically elegant for a mineral formula, though the single universal tint limits its audience.

normalcombination Fragrance Free

Derm-Developed Retinol Starter

NeoStrata retinoid

Correct Comprehensive Retinol 0.3% Night Serum

NeoStrata's Comprehensive Retinol 0.3% Night Serum is a thoughtfully engineered retinol for people who want results without recklessness — pairing stabilized retinol with the brand's signature NeoGlucosamine in a silky delivery system that makes retinization about as comfortable as it gets. At $82.50, it's a premium ask, but the science pedigree behind it is hard to match.

normalcombination Fragrance Free

Derm-Office Sun Defense

NeoStrata sunscreen

Defend Sheer Physical Protection SPF 50

One of the most scientifically complete mineral sunscreens available: mineral UV filters for UVA/UVB, iron oxides for visible light, and a PHA-antioxidant system for free radical defense. The price is premium, but the photoprotection philosophy is best-in-class.

normalcombination Fragrance Free

NeoStrata moisturizer

Restore Bionic Face Cream PHA 12

The quiet overachiever of NeoStrata's lineup — a rich, utterly gentle face cream that delivers 12% acid exfoliation so smoothly that sensitive and rosacea-prone skin actually thrives on it. The small jar and premium price sting, but the formulation quality from the inventors of PHA technology is in a class of its own.

drysensitive Fragrance Free

Body Exfoliation Workhorse

NeoStrata exfoliant

Glycolic Renewal Smoothing Lotion 10 AHA

NeoStrata's body-focused glycolic lotion brings the same pharmaceutical-grade AHA science to your arms, legs, and chest that the Smoothing Cream delivers to your face. At 200 mL for $55, it's dramatically better value than the cream, and for anyone battling keratosis pilaris, crepey texture, or years of sun damage below the neck, it's one of the most effective daily treatments available.

normalcombination Fragrance Free

Collagen Science Pioneer

NeoStrata serum

Correct Firming Collagen Booster

A genuinely sophisticated anti-aging serum from the brand that discovered AHAs, addressing collagen loss through three complementary pathways: peptide signaling, matrix reinforcement, and collagen protection. The science is real, but the alcohol and essential oils are puzzling choices from a dermatology-rooted brand.

normalcombination Paraben Free

AHA Pioneer's Gold Standard

NeoStrata exfoliant

Glycolic Renewal Smoothing Cream 10% AHA

NeoStrata's Glycolic Renewal Smoothing Cream is what happens when the scientists who invented AHA skincare make a product for daily use: 10% exfoliating acid that feels like a moisturizer, delivers like a treatment, and carries five decades of research behind it. The small jar and premium price sting, but the pedigree is unmatched.

normalcombination Fragrance Free

Heavy-Duty Acid Specialist

NeoStrata body-care

Problem Dry Skin Cream PHA 20

The closest thing to NeoStrata's original laboratory breakthrough in a consumer tube. This 20% multi-acid body cream is an absolute powerhouse for calloused heels, keratosis pilaris, and stubbornly rough skin — a purpose-built specialist from the brand that invented the science behind it.

drynormal Fragrance Free

NeoStrata moisturizer

Face Cream Plus AHA 15

A veteran glycolic acid cream from the brand that invented AHA skincare — no trends, no gimmicks, just 15% glycolic in an emollient base that has quietly delivered results for users who've stuck with it for a decade or more. Not for beginners, but for experienced acid users, this is the real deal.

normaldry Fragrance Free

Triple-Acid Pore Clarifier

NeoStrata cleanser

Mandelic Clarifying Cleanser

A smartly formulated triple-acid cleanser from the brand that literally wrote the textbook on hydroxy acids. The mandelic-salicylic-gluconolactone trio delivers genuine pore-clarifying results for oily skin, and at $34 for 200mL, the value is strong — though dry and sensitive skin types should steer well clear.

oilycombination Fragrance Free

Three-Depth Volumizer

NeoStrata serum

Tri-Therapy Lifting Serum

A three-pronged anti-aging serum that targets volume loss, hydration, and surface texture at different skin depths simultaneously. The proprietary Aminofil technology is intriguing and the formula is exceptionally gentle, but at $100 per ounce with fragrance components and limited independent research on its star ingredient, the value proposition requires careful consideration.

normaldry Paraben Free

Collagen Science Pioneer

NeoStrata serum

Firming Collagen Booster Serum

A scientifically grounded collagen serum from the brand that literally invented hydroxy acid skincare. The triple-mechanism formula with patented NeoGlucosamine, Matrixyl 3000, and collagen precursor amino acids delivers real firming results over time — but the denatured alcohol and essential oils feel like an outdated formulation choice for a brand this smart.

normalcombination Paraben Free

Multi-Pathway Brightening Powerhouse

NeoStrata serum

Enlighten Illuminating Serum

A scientifically ambitious brightening serum that attacks hyperpigmentation from five angles simultaneously, backed by genuine dermatological expertise. The formulation strategy is brilliant; the execution is undermined by alcohol, botanical allergens, and a price that demands perfection.

normalcombination Paraben Free

★★★★★

4.3 (400)

$88.00